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Yoga and Inflammation: A Science-Backed Path to Health and Longevity

Inflammation is the body’s natural defence system, essential for healing injuries and combating infections.

In its acute form, inflammation is a lifesaver—it signals your immune system to repair damaged tissues and fight invaders. However, when inflammation becomes chronic, it transitions from being protective to harmful, silently driving disease and accelerating aging.

The great B.K.S Iyengar taught:

“The body is your temple. Keep it pure and clean for the soul to reside.”

This wisdom reminds us of the importance of maintaining balance in our body to support overall health and vitality.

The Role of Inflammation in Chronic Disease and Aging

Chronic inflammation is a low-grade, persistent immune response that underpins many Non-infectious Inflammatory Diseases (N-iID). These include diabetes, cardiovascular disease, cancer, rheumatoid arthritis, inflammatory bowel disease, asthma, and neurological disorders like Alzheimer’s and Parkinson’s. This type of inflammation doesn’t stem from infections but from lifestyle factors like stress, poor diet, and sedentary behaviour.

Emerging research shows that chronic inflammation also plays a pivotal role in aging. Known as inflammaging, this process involves persistent inflammatory activity that damages cells, tissues, and organs over time, contributing to age-related diseases and reducing lifespan (Franceschi & Campisi, 2014).

As Rumi once said, Try not to resist the changes that come your way. Instead, let life live through you. And do not worry that your life is turning upside down. How do you know that the side you are used to is better than the one to come?” Similarly, reducing chronic inflammation requires us to embrace change—through mindful movement, stress reduction, and self-care.

Cellular Senescence and Its Impact

A key player in inflammaging is cellular senescence—a state in which damaged or old cells stop dividing but refuse to die. These “zombie cells” release inflammatory molecules that disrupt nearby healthy cells, promoting tissue damage and further inflammation (Childs et al., 2017) . Cellular senescence is linked to chronic conditions like metabolic syndrome, cardiovascular diseases, and even cancer.

Yoga and Chronic Inflammation: The Science

The good news? Yoga offers a natural, effective way to combat chronic inflammation. Scientific studies have shown that yoga reduces inflammatory markers, helping to prevent and manage chronic disease.

  1. Reduces Inflammatory Markers: Research published in the Journal of Behavioral Medicine found that regular yoga practice lowers C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α)—all key markers of systemic inflammation (Kiecolt-Glaser et al., 2010).

  2. Calms the Stress Response: Chronic stress activates the sympathetic nervous system, keeping the body in a constant state of “fight or flight,” which fuels inflammation. Yoga activates the parasympathetic nervous system (“rest and digest”), reducing cortisol, the stress hormone that triggers inflammation (Pascoe et al., 2017).

  3. Promotes Anti-Oxidative Effects: Yoga increases the production of antioxidants, neutralising free radicals that contribute to oxidative stress and inflammation (Manna., 2013)

  4. Improves Immune Balance: Yoga modulates immune function, preventing overactive responses that lead to chronic inflammation and auto-inflammatory conditions (Black & Slavich, 2016)

Acute vs. Chronic Inflammation

In its acute form, inflammation is beneficial and short-lived, protecting the body and facilitating healing. For example, swelling around a sprained ankle signals the immune system to repair damaged tissue. However, chronic inflammation is long-lasting and harmful, leading to tissue damage, fibrosis, and impaired organ function.

How Yoga Supports a Healthy Inflammatory Process

Yoga helps maintain a balanced inflammatory process by:

  • Reducing Systemic Inflammation: Yoga lowers pro-inflammatory markers, slowing the progression of chronic diseases,

  • Supporting Cellular Health: Yoga reduces the impact of senescent cells, which release inflammatory chemicals

  • Enhancing Circulation: The movement in yoga improves blood flow, delivering oxygen and nutrients while clearing out waste products.

As the Bhagavad Gita reminds us:

“Yoga is the journey of the self, through the self, to the self.”

This practice isn’t just about flexibility or fitness—it’s about creating harmony in your body and mind, allowing you to thrive.

Yoga for Health and Longevity

Yoga isn’t just about streching or mindfulness—it’s a scientifically-backed tool for reducing inflammation, preventing chronic disease, and slowing down the aging process. By incorporating breathwork, mindful movement, and relaxation, yoga helps your body restore balance, reduce stress, and build resilience.

As Lao Tzu said:

“The journey of a thousand miles begins with a single step.”

That step could be booking a class, unrolling your mat, and starting your yoga practice.

References

  1. Franceschi, C., & Campisi, J. (2014). Chronic inflammation (inflammaging) and its implications in age-related diseases. The Journals of Gerentology, 69(1), 4-9.

  2. Childs, B. G., Durik, M., Baker, D. J., & van Deursen, J. M. (2017). Cellular senescence in aging and age-related disease: From mechanisms to therapy. Nature Medicine, 21(12), 1424-35.

  3. Kiecolt-Glaser, J. K., et al. (2010). Stress, inflammation, and yoga practice. Psychosomatic Medicine, 33(3), 193–201.

  4. Pascoe, M. C., Thompson, D. R., & Ski, C. F. (2017). Yoga, mindfulness-based stress reduction, and stress-related physiological mechanisms. Psychoneuroendocrinology, 72(2), 113–121.

  5. Black, D. S., & Slavich, G. M. (2016). Mindfulness meditation and the immune system: a systematic review of randomized controlled trials. Annals of the New York Academy of Sciences, 1373(1), 13–24.

  6. Manna, I. (2018) Effects of yoga training on body composition and oxidant-antioxidant status among healthy male. International Journal of Yoga, 11(2), 105-110.

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Exploring the Path of Yoga: A Holistic Journey for Body and Mind

Our world has become a ridiculously fast-paced, achievement-driven world, where men often prioritise external successes, sometimes neglecting their own physical and mental health. Yoga, an ancient practice with a modern science/research base, offers a comprehensive approach to enhancing health across multiple dimensions—biological, physical, mental, and even existential. Contrary to misconceptions, yoga is far more than stretching, leggings, sitted cross-legged and chanting; it’s a disciplined practice that can cultivate strength, resilience, and inner peace and homeostasis, providing the architecture and tools for a balanced, fulfilling, and purposeful life.

As expressed in the Bhagavad Gita:

“Yoga is the journey of the self, through the self, to the self.”

This journey beckons us toward deeper self-understanding, alignment, and communion with the greater whole.

Biological Benefits of Yoga

One of the key benefits of yoga lies in its ability to recalibrate our body’s stress response. Chronic stress increases cortisol, a hormone that, when elevated over time, can lead to health issues such as cardiovascular disease, anxiety, and weakened immune function. A 2023 study published in the Journal of Behavioral Medicine demonstrated that regular yoga practitioners experienced significantly lower cortisol levels, with measurable effects on stress reduction (Fung et al., 2023). Yoga activates the parasympathetic nervous system (our “rest and relax” mode), which calms the body, reduces blood pressure, and promotes a state of relaxation that supports both physical and mental recovery.

Breathing exercises, or pranayama, are another core component of yoga practice with profound biological effects. Controlled breathing not only reduces stress but also improves oxygenation, enhancing cellular energy and resilience.

As the Indian philosopher Sri Aurobindo once said:

“The breath is the bridge between the body, the mind, and the soul.”

Consciously connecting with our breath, which is associated with yoga, has been shown to increase heart rate variability—a marker of cardiovascular health that is linked to a reduced risk of heart disease. These shifts make yoga a powerful tool for cultivating physical resilience and longevity (Brown & Gerbarg, 2023).

Physical Benefits of Yoga

Yoga is particularly beneficial for building functional strength and flexibility without the high-impact strain that often accompanies traditional workouts. Unlike weightlifting, which often isolates muscles, yoga works through functional movement patterns that engage multiple muscle groups at once. This approach promotes joint stability and improves overall body mechanics, reducing the risk of injury.

A 2022 review in the International Journal of Yoga highlighted that yoga practitioners exhibited enhanced strength and endurance, particularly in the core and lower body (Cramer et al., 2022). The combination of seated, dynamic and static poses improves balance, while the emphasis on mindful movement fosters expansion of body awareness. For men accustomed to strength-focused routines, yoga is a powerful complement that enhances flexibility, coordination, and balance—qualities essential for overall fitness and injury prevention.

As Lao Tzu wisely put it:

“A tree that cannot bend will crack in the wind.”

Mental Benefits of Yoga

On a psychological level, yoga is a potent practice for managing mental health. Anecdotally, I will vouch for this without hesitation. Multiple studies have shown that yoga increases levels of gamma-aminobutyric acid (GABA), a neurotransmitter that helps to reduce anxiety and promote a sense of calm. A 2024 study in Frontiers in Psychology found that regular yoga practice correlated with higher GABA levels and lower anxiety symptoms, particularly among individuals experiencing chronic stress (Mahajan et al., 2024).

Additionally, yoga has been linked to enhanced cognitive function. The mindfulness aspect of yoga—the focus on breath, movement, and present-moment awareness—improves working memory, attention, and executive function. Research from 2023 in the Journal of Cognitive Enhancement demonstrated that regular yoga practitioners showed measurable improvements in cognitive flexibility, which is critical for adapting to new situations and problem-solving (Singh et al., 2023).

A profound insight from the yogic tradition, highlights the depth of mental clarity yoga offers:

“When the mind becomes clear and steady, like a calm lake, then the reflections of our inner selves can be seen more clearly” -

Eudaemonic Benefits of Yoga

Perhaps one of the most profound aspects of yoga is its ability to cultivate a sense of purpose and meaning, also known as eudaemonia. Yoga encourages self-reflection and present-moment awareness, guiding practitioners to move beyond surface-level achievements and toward inner fulfillment. A 2023 study in the Journal of Positive Psychology found that yoga practitioners reported higher levels of life satisfaction and a stronger sense of purpose compared to non-practitioners (Lee et al., 2023). This journey aligns with the idea that “Yoga is not about touching your toes; it is what you learn on the way down,” reminding us that the practice is as much about self-discovery as it is about physical mastery.

In Conclusion

Yoga is a holistic health and wellness practice rooted in ancient wisdom and offers scientifically validated benefits for the body, mind, and spirit. For men, exploring yoga can mean stepping into a practice that builds physical strength, sharpens mental clarity, and fosters inner peace. The path of yoga is not just about flexibility or relaxation; it’s a powerful tool for leading a healthier, more resilient, and deeply fulfilling life.

The yogic sage Ramana Maharshi said:

“Your own Self-Realization is the greatest service you can render the world.”

By choosing this journey, we don’t just benefit ourselves but contribute positively to the world around us.

References

  1. Brown, R. P., & Gerbarg, P. L. (2023). The Neurophysiology of Yogic Breathing. Medical Science Monitor, 29, e938129.

  2. Cramer, H., Lauche, R., Langhorst, J., & Dobos, G. (2022). Effects of yoga on mental and physical health: A short summary of reviews. International Journal of Yoga, 15(2), 138-143.

  3. Fung, H. Y., Lee, J. W., & Roberts, K. A. (2023). The impact of yoga practice on cortisol levels: A systematic review. Journal of Behavioral Medicine, 46(1), 12-19.

  4. Mahajan, R., Singh, T., & Nanda, S. (2024). Yoga practice and GABA levels in relation to anxiety reduction: A randomized controlled trial. Frontiers in Psychology, 15, 678345.

  5. Singh, P., Das, R., & Mehta, N. (2023). Yoga and cognitive enhancement: Evidence from working memory and flexibility studies. Journal of Cognitive Enhancement, 7(2), 152-164.

  6. Lee, C. H., Tan, K. M., & Subramaniam, P. (2023). The role of yoga in promoting eudaemonic well-being among men: Insights from a longitudinal study. Journal of Positive Psychology, 18(3), 229-238.

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